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Internalized TSH receptors en route to the TGN induce local G s -protein signaling and gene transcription

Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

J Gen Physiol 94:911935 Dhar-Chowdhury P, Harrell MD, Han SY, Jankowska D, Parachuru L, Morrissey A, Srivastava S, Liu W, Malester B, Yoshida H (2005) The glycolytic enzymes, glyceraldehyde-3-phosphate dehydrogenase, triose-phosphate isomerase, and pyruvate kinase are components of the KATP channel macromolecular complex and regulate its function

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This discovery will help doctors better diagnose this rare genetic disorder and open the door to new treatments