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This GPX enzyme requires selenium

The carotenoids, such as -carotene, work as potent radical scavengers, neutralising ROS and protecting the intestinal mucosa from oxidative damage [353,354]

In an in vivo model, it showed the potential to arrest the cell cycle, suppress mitosis in tumor, endorse apoptosis, down-regulate pro-survival transcription factors (survivin, Bcl-2, phospho-Akt, c-Myc, mTOR, EGFR, and VEGF), and increase p21/WAF1 activation [230]

1 NAFLD is most commonly diagnosed in overweight and obese individuals, particularly those with metabolic syndromes including type 2 diabetes (T2D) and dyslipidemia