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51, Issue 19, pp

4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release

In the context of hereditary disorders related to copper metabolism, mutations in the ATP7A and ATP7B genes result in Menkes disease and Wilsons disease, respectively, both of which are marked by impaired transmembrane transport of copper ions, potentially resulting in copper accumulation across various organs [60, 206]

Even though the main function of the kidney is to excrete waste products from the bloodstream, it is important to mention that the kidney is also a major endocrine organ

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