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Use under clinical supervision as part of a comprehensive body composition or vitality protocol

(2.1, 2.2) Initiate folic acid 400 mcg to 1000 mcg orally, once daily, beginning 7 days prior to the first dose of pemetrexed for injection and continue until 21 days after the last dose of pemetrexed for injection

As CMS states, it is used to evaluate physician/non-physician services in some specific instances

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