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These results indicate that FMT can effectively enhance GR activity through FAD, improve antioxidant capacity, and maintain redox homeostasis in the body

the hypothalamicpituitaryadrenal axis is altered, and the normal negative feedback loop that suppresses the production of corticotrophin-releasing (CRH) and adrenocorticotropic hormone (ACTH) release in response to high cortisol is reduced

In the absence of obvious pathology to account for these symptoms, IC should be considered in the differential diagnosis (MacDiarmid and Sand, 2007

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If the breakdown process overtakes the rebuilding one, density and bone strength reduce