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Discovery of 4-[(5-arylidene-4-oxothiazolidin-3-yl)methyl]benzoic acid derivatives active as novel potent allosteric inhibitors of protein tyrosine phosphatase 1B in silico studies and in vitro evaluation as insulinomimetic and anti-inflammatory agents Eur

Disclosures: Jacquelin Blomker: Nothing to Disclose, Pavithra Ramakrishnan: Nothing to Disclose, Katherine Cooke: Nothing to Disclose, Virginia Hsiao: Nothing to Disclose, Jessica Makori: Nothing to Disclose, Claire Collins: Nothing to Disclose, Mary McConville: Nothing to Disclose, Jena Benson: Nothing to Disclose, Katie McLaughlin: Nothing to Disclose, Rachel Vogel: Nothing to Disclose, Taylor Bowler: Nothing to Disclose, Deanna Teoh: Tesaro/GSK: Grant/Research Support, Moderna: Grant/Research Support, Jounce Therapeutics: Grant/Research Support, Asieris: Advisor, Elizabeth Aby: United Health Care Group: Stock - publicly traded company, Medtronic: Stock - publicly traded company 944 THE BURDEN OF STEATOTIC LIVER DISEASE IN CROATIAN VETERANS THREE DECADES AFTER THE WAR Tatjana Reic 1 Ana Visic 1 Magda Pletikosa Pavic 2 Diana Nonkovic 3 Ivona Reic 1 Anna Mrzljak 4 , 1 Croatian Society for Liver Diseases Hepatos, 2 Teaching Institute for the Public Health Split - Dalmatia County, 3 Teaching Institute for Public Health Split - Dalmatia County, 4 University Hospital Center Zagreb Background: Croatia is currently the only EU country with a large war veteran population (11%), making it the precursor to future EU challenges

This should be of interest in the development of new therapeutic modalities designed to improve anticancer chemotherapy

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