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Taken together, we speculate that not only reduced GPx4 expression levels but also loss of GPx4 activity play a crucial role in COPD pathogenesis

We also examined the effect of succinylacetone (SA), an inhibitor of haem biosynthesis (Fig

The intra-cellular GSH level depends upon the equilibrium between the processes, during which it is consumed and on its biosynthesis, which, in turn, is limited by the availability of cysteine

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