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Micronutrient deficiencies are prevalent among cancer patients due to factors such as the disease itself, treatment side effects, reduced dietary intake, and malabsorption

doi: 10.1016/S0305-4179(01)00055-9

Even though the BBB is a highly selective membrane intended to protect the brain from toxins and invading pathogens, despite its semipermeable nature, the BBB is mostly impenetrable to most drugs, especially large or hydrophilic molecules, which restrict their entry into the brain and bloodstream