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Data processing and statistical analysis The LCMS/MS data were processed via MassHunter Quantitative Analysis software (version B.06.00, build 6.0.388.0) to quantify the individual metabolite levels relative to the stable isotopes added 25,26

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This asymmetry would become even more pronounced upon phosphorylation of the serine residues in LIRup

Ultra Pure Wateris crucial to our nanotechnology formulation. We remove all impurities and the non dissociated colloidal matter, gas and organic matter in the water to a very low level. Pure water is measured by Megohms of resistivity to electrical current. The use of ultra-pure water in industry includes pure water as a rinse bath for computer chip manufacturing. The theoretical maximum is 18.2 megohm. Our use includes ultra-pure water with a "cleanliness" of over 17.5 megohm