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doi: 10.1111/joim.2013.274.issue-1 217 HuSHuYYanW

For these cases, PSEN1, PSEN2, and APP are considered mandatory genes for analysis (Ibanez et al., 2021

Am J Physiol 1998

4-HNE can form covalent bonds with proteins, DNA, and phospholipids, thereby disrupting cellular functions and playing a role in the pathogenesis of various diseases [144]