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Some reports have shown serum albumin levels as a biomarker for CHE [21, 134], and others suggested several candidate markers including vitamin D levels and neuroinflammation- and neuroinjury-related markers such as S100B, neurofilament light chain, and glial fibrillary acidic protein [135,136,137,138]

However, studies confirm that glutathione is the most s ignificant antioxidant in the human body due to its regenerative power

Freeburn RW, Armstrong L, Millar AB (2005) Cultured alveolar macrophages from patients with idiopathic pulmonary fibrosis (IPF) show dysregulation of lipopolysaccharide-induced tumor necrosis factor-alpha (TNF-alpha) and interleukin-10 (IL-10) inductions

The test was performed three times to ensure accuracy

Regulators of PINK1 localization are potential targets for therapeutic approaches to modulate mitophagy, Chief among them is ATPase family AAA domain containing 3A (ATAD3A), a protein that regulates PINK1 importation and degradation, and autophagy and beclin 1 regulator 1 (AMBRA1) which can inhibit the action of ATAD3A and promote PINK1 stabilization on the outer mitochondrial membrane (Di Rienzo et al., 2022)