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Alternatively, PZA can be initially oxidized to 5-hydroxy-pyrazinamide (5-OH-PZA) by XO, followed by amidase-mediated hydrolysis to 5-OH-PA

S., & Bhopalwala, A

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In contrast, resistant WK ducks showed a significant increase in IgM (though lower than in susceptible WK ducks) alongside stable IgG and IgA ( p 0.05)

More studies should be conducted to investigate whether the observed increases in cytokines IFN-, TNF-, IL-2, and decrease in IL-10 found in granuloma supernatants is indeed the cause of the decreased burden of mycobacterial