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Description

An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis

Lysis was induced by recombinant tPA (final concentration, 60 ng/mL, Boehringer Ingelheim, Ingelheim, Germany) and involved mixing citrated plasma with calcium chloride (final concentration, 15 mmol/L), human tissue factor (Innovin, Dade Behring, final concentration, 0.6 pmol/L ), and phospholipid vesicles (final concentration, 12 mol/L), all diluted in Tris-buffered saline

It binds with copper ions and plays an important role in supporting tissue remodeling, wound healing, and regenerative processes within the body

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