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Therefore, we summarize the current knowledge regarding the mechanisms involved in the regulation of ferroptosis for further discussion of its role in the pathogenesis and prognosis of skin diseases

Studies in both normal healing and delayed healing models have shown improvements in callus volume, mineralization, bone mineral content, rate of successful union, and mechanical strength at fracture sites

These distinct mechanisms may include systemic dysfunction-induced neurologic injury, renin-angiotensin system (RAS) dysfunction, immune dysfunction, and direct viral invasion of the nervous system, as elaborated and summarized in Table 1 [55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71] and Fig

10.1093/jmcb/mjz060 64 LiuY.GuW

14 Using the MFIS as the primary outcome measure, 144 individuals were enrolled and assessed after 5 weeks of medication exposure