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Description

Resistance has developed to both first- and third- generation inhibitors, but the underlying mechanisms remain unclear [25]

High concentrations of cytotoxic BAs (e.g., DCA) can drive microbial transcriptional reprogramming, including upregulation of efflux pumps and stress response genes, and alterations in core metabolism and BA-modifying enzyme expression (122)

The Protocol Components of LIPO-C with added B12: Lipo-C Compound : A specialized lipotropic combination researched for its role in cellular fat oxidation, lipid export optimization, and methyl donor signaling pathways