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Nrf2, which can induce the expression of phase II detoxifying enzyme-encoding genes through antioxidant response elements (AREs), was defined as a master regulator of antioxidant systems in 1997

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Tempol (4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) improved endothelial function in Zucker diabetic fatty rats and in db/db mice [49]

Chronic administration of low dose aspirin alleviates ASD-like behaviors and activates AMPK in valproic acid-exposed rats