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Blood Tests Complete blood count (CBC): Shows macrocytic anemia Peripheral blood smear: Large red blood cells Serum vitamin B12 levels Specific Diagnostic Tests Intrinsic factor antibody test Parietal cell antibody test Serum methylmalonic acid (MMA) Homocysteine levels Additional Tests Bone marrow examination (rare cases) Treatment of Pernicious Anemia Pernicious anemia requires lifelong vitamin B12 replacement therapy

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