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doi:10.1016/j.heares.2010.09.006

Pernicious anemia low B-12 due to loss of stomach cells that make intrinsic factor

The constellation of anemia, skeletal deformities, organomegaly, and iron-related complications underscores the need for a multidisciplinary approach in managing Thalassemia, aiming not only at correcting anemia but also at preventing the progression of end-organ damage and preserving quality of life