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Feature · Product Review
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Description

Such variant-induced structural alterations can affect the interaction of small-molecule drugs, potentially impacting their therapeutic efficacy

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Consistently, chromosome-spread analyses showed that the premature cohesion loss induced by Sororin depletion was rescued by exogenous expression of wild-type Sororin-GFP or Sororin-SFB, but not by the WA/EK or FA/FA mutants, in both HeLa and RPE-1 cells (Fig

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