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Description

Ohnishi et al., 2003

Abstract Neutrophils are essential components of the innate immune system that defend against the invading pathogens, such as bacteria, viruses, and fungi, as well as having regulatory roles in various conditions, including tissue repair, cancer immunity, and inflammation modulation

C., Guo, L

The protective effect is mainly due to inhibition of PDH (pyruvate dehydrogenase) and pyruvate influx into mitochondria, thereby reducing Krebs cycle turnover and mito-ROS production (114)