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Alterations[81] in the intestinal microbiota can lead to abnormal immune function in the small intestine, which mediates inflammation following brain injury and plays a crucial role in triggering brain-gut axis disorders[82].A recent study discovered that pro-inflammatory the triggering receptor expressed on myeloid cell 1 (TREM1) signaling conveyed by gut-derived macrophages is transported to the brain and plays a significant role in the pathophysiology of secondary brain injury following CA/CPR[83]

Resveratrol prevents cognitive impairment in type 2 diabetic mice by upregulating Nrf2 expression and transcriptional level

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