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Thanks for that info ..it's really useful how does one know if the dose of 75mcg is right ...what clues are there to suggest that an increment up to 87.5mcg would be required Mix of symptoms and test results Test correctly..early morning and last dose levothyroxine 24 hours before test Aiming for Ft4 and Ft3 at least 50-60% through range Essential to maintain OPTIMAL vitamin levels for good conversion of Ft4 to Ft3 Likely to benefit from strictly gluten free diet (Test for coeliac first) Consider trialing dairy free diet too in few months time Look at testing for SIBO and H Pylori if gut issues dont resolve when Levo dose and vitamins optimal and gluten free/dairy free should be able to ween slowly off PPI then Your mum is legally entitled to copies of all her test results and ranges done via NHS The best way to get access to current and historic blood test results is to register for online access to your medical record and blood test results UK GP practices are supposed to offer everyone online access for blood test results