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In this review article, we aimed to update the understanding of the possible roles of HDACs in the pathophysiology of epilepsy, discuss the likely regulatory mechanisms of these enzymes and summarize the recent progress in the development of HDACi in epilepsy rodent models and patients

Through testing of 12 EN25 analogs that were commercially obtained through Enamine, we found that EN25-7 and EN25-8 showed the best inhibitory potency against GCL with IC50s of 8.9 and 6.8 M, respectively (Fig

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Human papillomavirus-16 E6 activates the pentose phosphate pathway to promote cervical cancer cell proliferation by inhibiting G6PD lactylation

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