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[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Hutabarat RM, Unadkat JD, Kushmerick P, Aitken ML, Slattery JT, Smith AL

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If side effects are mild and go away quickly, they usually dont require a doctors visit

While the immune system reacts abnormally to progesterone, many symptoms are driven by mast cell activation and histamine release rather than classic autoantibodies, which is why antihistamines are often effective