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Specifically, an increase in pro-inflammatory taxa and a reduction in beneficial bacteria significantly drive its core pathophysiological processes, such as HA, IR, and inflammation

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mild, moderate, severe, and very severe ( In one survey of 1418 ME/CFS patients ( Diagnostic criteria for ME/CFS The original neurological classification of ME/CFS In 1969, the World Health Organisation (WHO) classified ME/CFS as a neurological disease ( Available diagnostic criteria Despite its high prevalence, there are still no universally accepted clinical criteria to characterise ME/CFS, making early and accurate diagnosis difficult ( Figure 3