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Upon transfection or transduction with genes encoding for one or multiple drug metabolizing enzyme genes, HepG2 cells have been shown to be a valuable model system to study the role of bioactivating enzymes in the cytotoxicity of toxicants (Vignati et al., 2005

doi: 10.1038/nrc1074

Antioxidants 13 , 460 (2024)

By maintaining hidden state connections across time steps, RNNs can retain information from previous inputs, making them highly effective for sequential data such as text, speech, and physiological signals [56, 57]