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Stability: This modification gives IGF-1 LR3 a significantly longer half-life, approximately 20 to 30 hours, compared to natural IGF-1, which typically lasts only 1215 minutes in circulation

This was attributed to spermidines ability to activate mitophagy and autophagy, helping maintain mitochondrial quality and preventing the accumulation of damaged mitochondria in heart tissue (Reference Eisenberg, Abdellatif and Schroeder80)

Estimates of odds ratios [95% confidence intervals (CIs)] are presented for interquartile range (IQR) increases in these parameters

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Supplemental testosterone had no effect on lower-body muscle function or health-related biomarkers. Meanwhile, peptides have been shown to increase muscle size and lean body mass, though to a lesser extent