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Lack of approval reflects insufficient human clinical trial data and incomplete evaluation of risks, dosing, and long-term effects

The cell adhesion signal peptide sequence arginine-glycine-aspartic acid (RGD) can guide cells to recognize the scaffold material, which helps maintain the cells phenotype and activity ( In vitro experiments have shown that collagen can promote the proliferation and differentiation of nerve cells and inhibit the proliferation of neurocollagen gliosis (OConnor et al., 2001

Besides that, it also increases the uptake of glucose to improve the insulin sensitivity

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