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Description

According to the previous literature, we isolated and identified 5 ingredients of FRP by silica gel TLC and recrystallization (Zhang et al., 2008)

M., & Strekalova, T

In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor

Thus, the use of this approach allowed to identify an original target, the protein kinase DYRK1B, suggesting that an inhibitor of this protein could present a possible senolytic activity 40