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Crucially, FDX1 emerged as a central regulator, as its depletion abolished protein lipoylation, suppressed cellular respiration, caused pyruvate and -ketoglutarate accumulation, reduced succinate levels, and stabilized Fe-S cluster proteins

In enzalutamide-resistant PCa cells, the expression of CPT1B is up-regulated, and the up-regulation of CPT1B increases the resistance of PCa cells to enzalutamide

Islet function in offspring of mothers on low-protein diet during gestation

Animals were housed in cages with dimensions of 90 60 50 cm, accommodating 56 rats per cage

48 hours after transfection, the genomic DNA were extract using DNeasy Blood & Tissue Kit (QIAGEN, USA)