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In a 12-week randomized clinical trial involving 300 obese adults, participants receiving 1 mg daily of AOD-9604 lost an average of 2.6 kg (approximately 5.7 pounds) compared to 0.8 kg (1.8 pounds) in the placebo group

Among women with menstrual-related migraines, using hormone therapy to minimize monthly declines in estrogen concentration may be effective in preventing migraine attacks (Calhoun 2009)

People on vegan or strict plant-based diets need a reliable source from fortified foods (nutritional yeast, fortified plant milks, certain breakfast cereals) or a supplement

People who are more insulin-resistant need a higher dose of insulin to maintain their blood glucose levels within the normal range

It is also used to manage sciatica pain (leg pain), back pain and general weakness in affected individuals