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Among 17,604 adults with overweight or obesity (BMI 27) and established cardiovascular disease but without diabetes, weekly semaglutide cut the primary composite of cardiovascular death, non-fatal heart attack or non-fatal stroke by about 20% reaching 6.5% of the semaglutide group versus 8.0% on placebo, a hazard ratio of 0.80 (95% CI 0.720.90) (PMID 37952131)

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