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Gozes group has found that ADNP mutations affect MT dynamics and inhibit its interactions with Tau [348, 349], producing a tauopathy-like phenotype manifested in increased GSK-3 activity, Tau hyper-phosphorylation, and cognitive deficiency [293]

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These effects could potentially be beneficial in treating various neurological conditions, though clinical evidence remains extremely limited

Oxidative stress can cause DNA damage and telomere shortening (95)

10.3390/nu16091273 89 MurakamiT.BodorE.BodorN