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In the case of depressive patients, physical activity and a healthy diet are also proven as significant factors to reduce anxiety and depressive behaviors [215]

These findings suggest that LT effectively alleviates the DHEA-induced imbalance in sex hormone metabolism in mice by lowering hyperandrogenism (T and LH) and prolactin levels, restoring the gonadotropin ratio (LH/FSH), and increasing progesterone secretion, indicating its potential for regulating hormone disorders

Another paper indicated that extensive necrosis occurred in APAP-treated JNK hepatocyte-specific knockout mice, and further demonstrating that combined activity of JNK1 and JNK2 can prevent APAP-induced necrosis by controlling the generation of oxidative stress [114]

Zafarullah, M., Li, W