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TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

Hydrolysis of homocysteine thiolactone results in the formation of Protein-Cys-S-S-homocysteinylation

To illustrate, such a mechanism could lead to the activation of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), as suggested by Ohta (2023), which is known to be involved in oxidative stress responses (Yu et al., 2021) and involves a basic leucine zipper (bZIP) transcription factor