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Given these findings and the altered bioenergetic profile indicative of mitochondrial dysfunction, a detailed investigation into mitochondrial functionality was undertaken

TESTING G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES G01N2800/00Detection or diagnosis of diseases G01N2800/52Predicting or monitoring the response to treatment, e.g

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At a concentration of 10 mM, exposure was found to cause profound intracellular Ca 2+ overload and significant Ca 2+ -dependent lytic cell death