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Epitalon is the tetrapeptide Ala-Glu-Asp-Gly (AEDG), studied as a reagent in cellular-aging research

Data availability Data that support the findings of this study have been deposited in the Gene Expression Omnibus (GEO) under the accession codes: ChIP-seq data, GSE125822 and RNA-seq data, GSE140274

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Moreover, infants with an increased colonization of Firmicutes and a decreased colonization of Bacteroidetes (corresponding to an increased Firmicutes -to- Bacteroidetes ratio), or a decreased colonization of Proteobacteria and Bifidobacteria are shown to be at increased risk of developing food allergies (188191)

153,154 The pathogenesis of DPN is driven primarily by metabolic disturbances characteristic of diabetes, including hyperglycemia and insulin resistance