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J Neurosci Res 92:12171226 Funding The authors declare that no funds, grants, or other support were received during the preparation of this manuscript

Somatostatin perspectives in congenital hyperinsulinism Congenital hyperinsulinism is a rare disease with a significant genetic component causing unregulated overproduction of insulin through defects in the insulin-releasing pathway

Higher levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) were found to be present, which is a marker for oxidative DNA damage, and when melatonin was introduced, there was an appreciable decrease in the levels of 8-OHdG, which shows that melatonin is a protective factor against ROS-induced DNA injuries (189)

Gramlich et al., 2015

However, that doesnt mean injections should be used casually or without guidance