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In NAFLD-induced liver injury, ACN attenuated oxidative stress and inflammation by three independent mechanisms: inhibition of lipogenesis by reducing sterol regulatory element binding protein-1c (SREBP-1c), promotion of lipolysis by induction of PPAR activity, and reduction of oxidative stress (Valenti et al., 2013)

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I 2 = 69.8%, p = 0.069), HOMA-IR (SMD: 0.51

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