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1457-C ASSESSMENT OF REGIONAL IMPACT ON THE PHARMACOKINETICS OF VIR-2218 (BRII-835) IN SUBJECTS WITH CHRONIC HEPATITIS B VIRUS INFECTION Yali Zhu 1 , Sneha Gupta 2 , Chunming Li 1 , Chong Zhu 1 , Xiaofei Chen 1 , Weihong Liu 1 and Ji Ma 1 , (1)Brii Biosciences, (2)Vir Biotechnology, Inc Background: VIR-2218 (also referred as BRII-835) is an investigational, N-acetylgalactosamine (GalNAc)conjugated RNA interference (RNAi) therapeutic that targets a region of the hepatitis B virus (HBV) genome that is common to all HBV viral RNA transcripts

372 Improvement in HT has also been observed in other dietary interventions, including elimination of gluten or lactose, energy restriction, and consumption of Nigella sativa, suggesting the potential benefit of diet as a complementary treatment for HT

Pathway enrichment analysis, detailed in Fig

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