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The clinical profile associated with mutations in PRKN, PINK1, and PARK7 typically includes classic motor symptoms of Parkinsonism that appear at a younger age, typically before or around 30 years, and are linked with a slower disease progression

These sexbased hormonal and developmental distinctions likely contribute to the observed disparity in PD risk, suggesting that biological sex should be considered in PD risk stratification and mechanistic research [76]

Injection training: patients receive hands-on training on subcutaneous self-injection technique, vial storage (refrigerated), and reconstitution if supplied lyophilized

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