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Additionally, AgNPs prepared with honey bee extract (1218 nm size) were used against colon cancer cells, which revealed anti-cancer activity (215)

A 2022 study in Diabetes, Obesity and Metabolism showed that NNMTi treatment combined with reduced-calorie diet "promoted dramatic whole-body adiposity and weight loss in diet-induced obese mice, rapidly normalizing" weight parameters

Future research must focus on establishing standardized treatment protocols and understanding which individuals are most likely to benefit, ensuring safer and more effective support for children on the autism spectrum

Theoretical concerns about chronic NNMT inhibition include effects on the metabolism of other quinolinium and methylpyridinium endogenous metabolites and on the broader cellular methylation landscape

It helps treat vitamin B12 deficiency and conditions like pernicious anemia