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In this type of scenario, where few things can bring a sense of control, a leader's biology is one of the few domains where they can still exert direct control

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Among them, the cytosolic enzyme nicotinamide N-methyltransferase (NNMT) has been newly discovered to regulate the levels of nicotinamide precursors required for NAD+ biosynthesis, and therefore plays a crucial role in regulating the NAD+ salvage pathway and cellular metabolism

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Hu JS, James G, Olson EN