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In SCA3, ASOs have been used either to decrease overall ATXN3 levels or to generate a truncated ATXN3 which lacks the polyQ expansion [280, 281]

The peptides referenced are research compounds not intended for human or veterinary use, and example values are not medical advice or personal-use instructions

iron (Galms et al

Metformin, a commonly prescribed medication for diabetes, is also associated with vitamin B12 deficiency Functional vitamin B12 deficiency Some people appear to have enough vitamin B12 in their blood, but they do not have the proteins they need to transport it between cells