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New research presented at the Endocrine Societys 2025 Annual Meeting (ENDO 2025) has revealed that tirzepatidea medication originally developed for weight loss and type 2 diabetesmay offer surprising benefits for men suffering from both obesity and functional hypogonadism (low testosterone due to metabolic causes)

Materials and Methods Plant Materials and Treatments The seeds of the tomato cultivar Zheza205 were grown on mixed soil in pots

256 Therefore, the administration of KD may be a potential approach to enhance the therapeutic efficacy of chemotherapy

By performing a GFP-Trap SUMOylation assay we found that TDP-43 PYNLS rescues the loss of SUMOylation observed when expressing TDP-43 NLSmut indicating that nuclear localization, and not the lysine (K) residues within the NLS, is required for stress-dependent TDP-43 SUMOylation (Fig

M., McDonald, J