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acyl type protecting groups for example, formyl, trifluoroacetyl, acetyl aromatic urethane type protecting groups for example benzyloxycarboyl (Cbz) and substituted Cbz aliphatic urethane protecting groups for example, t-butyloxycarbonyl (Boc the side chain protecting group remains intact during coupling and is not split off during the deprotection of the amino-terminus protecting group or during coupling

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Wu J, Wang Y, Jiang R, Xue R, Yin X, Wu M, Meng Q

Abstract Purpose To elucidate mechanisms of renal excretion of pudexacianinium (ASP5354) and evaluate renal impairment effects on pharmacokinetics, safety, and tolerability of pudexacianinium