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Schedule: Daily injections for 812 weeks (optional extension up to 16 weeks ), followed by a 24 week break for protocol cycling

The TME of pancreatic cancer is highly disordered, and in stark contrast to the more organized and clearly defined tumor masses found in some other cancers, the scattered cancer cell nests are surrounded by a rich stroma interspersed with CAFs and immune cells, which is a hallmark of pancreatic cancer [11]