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Furthermore, TERT promoter mutations activate telomerase, enabling replicative immortality, whereas copy number alterations exacerbate the dysregulation of key cellular pathways

By inhibiting tyrosinase activity, glutathione decreases melanin production, reducing hyperpigmentation and dark spots

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These systems exhibit considerable versatility in terms of composition, functional properties, and mechanisms of action

These processes converge on synaptic dysfunction and reduced synaptic plasticity, which may underlie both the persistence of depressive symptoms, and the high rates of treatment resistance observed in LLD