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Currently, CB-839 has been in phase I and phase II clinical trials on AML (ClinicalTrials.gov: NCT02071927, ClinicalTrials.gov: NCT03047993)

USA 104 , 58895894 (2007)

In normal cells, however, epitalon led to a significant increase in telomerase activity by fourfold in IBR.3 treated cells compared to untreated, and 26-fold increase in treated HMEC cells compared to untreated

Simultaneously, GHK-Cu stimulates the production of decorin, a proteoglycan that regulates collagen fibril assembly and organization, ensuring that newly synthesized collagen forms properly organized matrices rather than disorganized scar tissue

Bibcode:1996Natur.379..632L