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GABA content was reduced compared to controls across anterior cingulate and occipital cortex and across the full sample of patients with recent or established schizophrenia

Tail vein blood (~5-10 l) was collected serially at 0, 30, 60, 90 and 120 min post-challenge through the tail-nick method (19) The blood collection procedure was approved by the Institutional Animal Care and Use Committee of City of Hope in accordance with the NIH Guidelines for Survival Blood Collection in Mice and Rats ( Blood glucose concentration was measured with an Accu-Chek Compact Plus glucometer (Roche Diagnostics Ltd.)

In the Fund Number and Account Number(s) field, input the relevant account details along with a daytime phone number for contact purposes

This regimen is considered the best option for inducing ferroptosis for due to reduced cystine, low levels of glutathione or antioxidant, and iron-loaded transferrin is an ideal substrate and condition for ROS generation in cell culture

Research Clinical trials are limited but growing